Sodium bicarbonate also is an active ingredient in antacid products used to relieve heartburn and treat acid indigestion. Managing Exposure to Sodium Bicarbonate Irritability and tetany have been associated with sodium bicarbonate-induced alkalosis or hypernatremia. Oakville, ON L6J 3J3 PRODUCT AND COMPANY IDENTIFICATION 1.1 Product identifiers Product name : Sodium bicarbonate Product Number : S5761 Brand : Sigma REACH No. Papile LA, Burstein J, Burstein R, Koffler H, Koops B "Relationship of intravenous sodium bicarbonate infusions and cerebral intraventricular hemorrhage." 2) Skin Contact Chicago, IL 60654 Toll free: 1.888.362.2007, VelocityEHS | Humantech These patients often present with an otherwise unexplained hypokalemic hypochloremic metabolic alkalosis. J Clin Gastroenterol 8 (1986): 454-6, 21. Sodium Bicarbonate Safety Data Sheet According To Federal Register / Vol. Due to greater permeability of the blood-brain barrier to hydrogen than to bicarbonate, the pH of cerebrospinal fluid may significantly decrease during sodium bicarbonate administration, which can cause mental stupor or coma. Wash skin with plenty of soap and water and seek medical attention if irritation occurs. 4) Ingestion Excess heat. Sodium bicarbonate is a common ingredient in cleaning, detergent and degreasing products. Sodium bicarbonate should be stored in a tightly closed container and placed in a cool, dry, well-ventilated area. Over-the-counter antacid products containing sodium bicarbonate … Inhalation Move to fresh air. Even though sodium bicarbonate is relatively safe compared to other chemicals in the workplace, as with any chemical, all unnecessary exposure should be avoided. Unlimited SDS Searches, 5 FREE Downloads, No Credit Card, The National Institute for Occupational Safety and Health (NIOSH), COVID-19 Workplace Standards Update: State OSHA Agencies Continue Development of Regulations to Protect Workers, OSHA Is Issuing Large Fines to Companies for COVID-19 Related Violations, VelocityEHS Offers HazCom & Chemical Safety Support for Emergency Responders, Businesses and Others Affected by Hurricane Delta, Coughing and sneezing if a high concentration of dust has been inhaled, Gastrointestinal irritation can occur if large amounts have been ingested, Mild irritation, such as redness and slight pain, may result from eye contact, In dry form, it’s typically non-irritating to intact skin; however, it can cause irritation to damaged skin when moisture is present. Applies to sodium bicarbonate: granule, solution, tablet. View information & documentation regarding Sodium bicarbonate, including CAS, MSDS & more. Sodium bicarbonate is broadly used as a physiological buffer in cell culture applications. J Pediatr 93 (1978): 834-6, 14. Toll free: 1.866.919.7922. Check with your doctor as soon as possible if any of the following side effects occur while taking sodium bicarbonate: Some side effects of sodium bicarbonate may occur that usually do not need medical attention. Jpn Heart J 31 (1990): 109-13, 4. [Ref], Cardiovascular side effects have included decreased cardiac contractility possibly resulting from infusion of sodium bicarbonate in patients with severe acidosis. Sodium bicarbonate (IUPAC name: sodium hydrogen carbonate), commonly known as baking soda or bicarbonate of soda, is a chemical compound with the formula NaHCO3. Acta Chir Scand Suppl 530 (1986): 97-9, 23. Last updated on Feb 19, 2020. Flush eyes with plenty of water and seek medical attention if irritation occurs. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Nephrol Dialysis Transplant 14 (1999): 452-4, 11. Sodium Bicarbonate Powder 10. Exposure to moist air or water. SODIUM BICARBONATE . 586 Argus Road Vacuuming or wet sweeping are recommended to avoid dispersing dust. Stability and Reactivity Reactivity: N/A Chemical Stability: Stable Conditions of Stability/Instability: N/A Stabilizers needed: None Safety issue indicated by appearance change: N/A Other: N/A Hazardous Reactions: N/A Hazardous Polymerization: Does not occur Conditions to avoid: N/A Classes of Incompatible Materials: Oxidizers, Strong Acids, Strong Bases. 02/02/2017 Date of Issue: 02/02/2017 Version: 2.0 SECTION 1: 02/02/2017 EN (English US) 1/6 IDENTIFICATION Sodium bicarbonate has many applications in the workplace as well, including being used in fire extinguishers or in an agricultural setting as a way to combat the growth of fungus on farms. Indian J Pediatr 45 (1978): 277-8, 16. Cooper DJ, Worthley LI "Adverse haemodynamic effects of sodium bicarbonate in metabolic acidosis." Arch Intern Med 136 (1976): 1179-80, 10. Suite 1750 1161 Oak Valley Dr. Product should be treated as a chemical and is not for consumption as it has been stored with other nonfood-grade chemicals. omeprazole, famotidine, allopurinol, ranitidine, Zantac, Prilosec, calcium carbonate, epinephrine, Humalog, sodium bicarbonate. Sodum bicarbonate has two pKas, 6.4 and 10.3. Toll free: 1.800.807.0783, Canada Application Sodium Bicarbonate Safety Data Sheet according to Federal Register / Vol. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. (NTP, 1992) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations … Potential Health Hazards from Sodium Bicarbonate. Astra USA, Westborough, MA. It is a salt composed of a sodium cation (Na ) and a bicarbonate anion (HCO3 ). Skin May be harmful if swallowed (H303). First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Take sodium bicarbonate as your doctor’s prescription instructs 2 3.The general recommendation for heartburn is 1/2 tsp. Suite 300 If the chemical has been contaminated, contact your state’s Environmental Protection Agency for disposal procedures specific to your area. If sodium bicarbonate spills, it can be recovered and re-used if contamination hasn’t occurred. Thomas SH, Stone CK "Acute toxicity from baking soda ingestion." The sodium bicarbonate is decomposed by heat producing sodium carbonate. Sodium Carbonate, Anhydrous (497-19-8) Listed on the United States TSCA (Toxic Substances Control Act) inventory SARA Section 311/312 Hazard Classes Health hazard - Skin corrosion or Irritation Health hazard - Serious eye damage or eye irritation Cellulitis, tissue necrosis, ulceration, or skin sloughing have possibly been the result of extravasation. Mastrangelo MR, Moore EW "Spontaneous rupture of the stomach in a healthy adult man after sodium bicarbonate ingestion." These effects have been associated with rapid or prolonged administration. Kennedy S "Sodium bicarbonate abuse in anorexia nervosa." Ann Intern Med 112 (1990): 492-8. Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. While sodium bicarbonate is generally not considered to be amongst the most harmful of chemicals, exposure to large amounts may result in some adverse health effects, such as: Safety Precautions When Handling Sodium Bicarbonate. Sodium bicarbonate, according to the National Institutes of Health Toxicology Data Network, has a low toxic risk. Medically reviewed by Drugs.com. Seek medical attention immediately if any breathing difficulty occurs. Conditions to Avoid Incompatible products. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Major Potential Hazard, High plausibility. 8. That dose is for individuals older than 12 years of age. [Ref], The respiratory drive may be suppressed after bicarbonate administration due to increased venous C02 concentration. [Ref], Nervous system side effects have included irritability, tetany, mental stupor, coma, and intraventricular hemorrhage.[Ref]. Okada H, Inoue T, Takahira S, Sugahara S, Nakamoto H, Suzuki H "Daytime hypertension, sleep apnea and metabolic alkalosis in a haemodialysis patient - the result of sodium bicarbonate abuse." Material Safety Data Sheet Sodium bicarbonate MSDS Section 1: Chemical Product and Company Identification Product Name: Sodium bicarbonate Catalog Codes: SLS3241, SLS2446, SLS3868 CAS#: 144-55-8 RTECS: VZ0950000 TSCA: TSCA 8(b) inventory: Sodium bicarbonate CI#: Not available. Side effects have rarely included intravascular volume expansion with resultant hyporeninemia and hypoaldosteronemia.[Ref]. Br J Psychiatry 149 (1986): 502-3, 5. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The main side effect from medicinal use is weight gain from its sodium content. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of carbon monoxide, carbon dioxide and sodium oxides. Am J Emerg Med 12 (1994): 57-9, 9. J Crit Care 9 (1994): 255-61, 18. These side effects may go away during treatment as your body adjusts to the medicine. Cutis 32 (1983): 65-6, 15. Brismar B, Strandberg A, Wiklund B "Stomach rupture following ingestion of sodium bicarbonate." 58 / Monday, March 26, 2012 / Rules and Regulations 09/13/2019 EN (English US) 5/6 Sodium Bicarbonate (144-55-8) LC50 fish 1 8250 - 9000 mg/l EC50 Daphnia 1 2350 mg/l Without adequate ventilation, worsened systemic acidosis could develop. A slow rate of administration of a properly diluted solution into a large bore needle and vein is recommended if IV administration is necessary. If this chemical gets into a worker’s eyes, it can cause mild to moderate irritation. [Ref], Urinary alkalinization from bicarbonate can cause a falsely positive colorimetric assay for protein. [Ref], Renal side effects have rarely included "False proteinuria". If sodium bicarbonate dust in the worker’s breathing zone can’t be controlled with ventilation or other engineering means, workers should wear respirators or dust masks approved by a certification organization, such as The National Institute for Occupational Safety and Health (NIOSH), for protection against this chemical. SAFETY DATA SHEET Version 4.6 Revision Date 02/26/2014 Print Date 03/20/2014 1. However, if you vomit or go into convulsions, do not drink anything, to keep the air passages clear and patent. Most Important Symptoms and Effects Both Acute and Delayed Arieff AI "Managing metabolic acidosis: update on the sodium bicarbonate controversy." Some experts recommend invasive hemodynamic monitoring in acidotic patients before the administration of bicarbonate. Lazebnik N, Iellin A, Michowitz M "Spontaneous rupture of the normal stomach after sodium bicarbonate ingestion." Page 1 of 4 Chief Medical Supplies Ltd. 411 – 19 Street, S. E. Calgary, AB., Canada. 77, No. Keep away from acids, excessive heat and moisture. © Copyright 2019 VelocityEHS. Scott Med J 34 (1989): 534-5. Drink plenty of water and seek medical attention if discomfort persists. Sodium hydrogen carbonate CAS 144-55-8 for analysis EMSURE® ACS,Reag.Ph Eur - Find MSDS or SDS, a COA, data sheets and more information. Carbon dioxide is an asphyxiant, and soda ash is an irritant. Rare cases of sodium bicarbonate abuse have been associated with features of Munchausen syndrome. It has a slightly salty, alkaline taste resembling that of washing soda (sodium carbonate). Do NOT induce vomiting. Gastroenterology 87 (1984): 1014-21, 20. M-D6-010 OSHA Vacated PELs: Sodium bicarbonate: No OSHA Vacated PELs are listed for this chemical. ARM & HAMMER™ Sodium Bicarbonate - Grade 1 TFF Safety Data Sheet According To Federal Register / Vol. [Ref], As an antacid, sodium bicarbonate, especially after excess food or liquid, can cause excess gas release (when combined with gastric acid). "Product Information. Inhalation of this chemical can lead to adverse effects such as respiratory tract irritation, coughing, shortness of breath, and pulmonary edema. Chronic ingestion of bicarbonate may rarely cause intravascular volume expansion with resultant hyporeninemia and hypoaldosteronemia. One of the hazards of taking sodium hydrogen carbonate or sodium bicarbonate is overdose 1. Side Effects & Safety When taken by mouth: Sodium bicarbonate is LIKELY SAFE when taken appropriately, short-term. 77, No. Pharmacotherapy 15 (1995): 660-4, 19. Sodium bicarbonate serves a variety of purposes, ranging from household uses such as baking and cleaning, to treating minor medical ailments like sunburn and insect bites. Sodium bicarbonate is the active ingredient in baking soda. EH&S Blog Health & Safety Safety with Sodium Bicarbonate, 222 Merchandise Mart Plaza Get medical attention immediately if symptoms occur. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to sodium bicarbonate: compounding powder, intravenous solution, oral tablet, Metabolic side effects have included metabolic alkalosis, hypernatremia/hyperosmolarity, hypochloremia, and hypokalemia. J Clin Psychiatry 49 (1988): 168, 3. Acta Neurol Scand 57 (1978): 239-47, 13. 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